PRODUCT CODE:

131014

Benzoic Acid PA-ACS

C₇H₆O₂

M.= 122,12	CAS [65-85-0]	EINECS 200-618-2
NC 2916 31 00	E -210

SYNONYMS: Benzenecarboxylic acid · Phenylformic acid ·
PHYSICAL DATA: White crystalline powder · Solubility in water at 20 ºC 2,9 g/l · M. P.: 122,4 ºC · B. P.: 249,2 ºC · Sublimation above 100 ºC · Flash P.: 121 ºC · K_a (25 ºC) 6,40 x 10^-5·
APPLICATIONS: Analytical reagent: USP 31 · BP 2008 · Ph. Eur. 6.0 · Primary chemical matter for acidimetric titrations · Food preservative · Preparation of benzoates, benzoyl compounds and dyes · Synthesis reagent: For use in the direct acylation of aniline to give benzanilide, see: Org. Synth. Coll. Vol., 1, 82 (1941) · For conversion to the mixed anhydride, by reaction with ethyl chloroformate, and use in the C-benzoylation of diethylmalonate , see ; Org. Synth. Coll.Vol., 4 , 285 (1963) · Electrophilic substitution of benzoic acid is exemplified by 3,5-disulphonylation with oleum and 3,5-dinitration with mixed nitric and sulphuric acids: Org. Synth. Coll. Vol., 3 , 288 y 337 (1955) · Birch reduction: Sodium in liquid ammonia containing ethanol: Org. Synth. Coll.Vol., 5 ,400 (1973). Reviews of the Birch reduction ; Q. Rev. Chem. Soc. 4 , 69 (1950); Chem. Rev. , 46 , 318 (1950) Org.React. , 23 , 1 (1976) · Reacts with 70% hydrogen peroxide in the presence of methanesulphonic acid to give the useful oxidising agent: peroxibenzoic acid: Org. Synth. Coll. Vol., 5 , 904 (1973) · A more convenient procedure for the conversion of aromatic acids to peroxyacids involves reaction with potassium persulphate in a two-phase system in presence of benzyl triethylammonium chloride: Synth. Commun., 18 , 2123 (1988) ·
BIBLIOGRAPHY: Merck Index 13 , 1092 · Sax BCL 750 · Safety 2 , 360 A · Römpp 8, 400 · BRETH: 669 · Beilstein 9 , 92 I , 54 II , 72 III , 360 IV, 273 · BRN : 636131 · Fieser 1 , 49 · ACS IX , 187 X , 200 · USP 31 · BP 2008 · Ph. Eur. 5.0 (2005) 6.0 (2008) · F.C.C. V , 6 · Directive 96/77/EC , 5 2008/84/EC ·

HAZARDOUS: RTECS: DG 0875000 · LD₅₀ oral rat 1700 mg/Kg · LD L₀ oral man 500 mg/Kg ·

R: 22-36
S: 24

SPECIFICATIONS:

Minimum assay (Acidim.)	99,5 %
Identity	IR p/t.
Melting range	122-123°C
MAXIMUM LIMIT OF IMPURITIES
Insoluble matter in CH₃OH	0,005 %
Residue on ignition (as SO₄)	0,005 %
Reducing substances to KMnO₄	p/t.
Chlorine compounds (as Cl)	0,005 %
Sulphur compounds (as S)	0,002 %
Heavy metals (as Pb)	0,0005 %
As	0,0003 %
Cu	0,001 %
Fe	0,001 %
Ni	0,001 %
Pb	0,001 %